Coeliac Disease: Glutens Create Negative Immune System Response

Coeliac Disease is a digestive disorder provoked by consumption of products containing gluten proteins, like bread, pasta and cookies composed of wheat, barley or rye grains.

This auto-immune disease treats these gluten proteins as toxins, and the body’s immune system cross reacts with tissue in the small intestine, creating an inflammatory reaction. This reaction leads to a shortening of the villi of the intestinal wall, which absorb nutrients into the body.

This lack of absorption of essential nutrients into the body can cause vitamin deficiencies that can deprive your brain and other bodily organs of vital nourishment needed for growth and continued sustainability of your body’s operating systems.

This disease has led to a multitude of products being created that are “Gluten Free” and specific diets have been created as well, to satisfy the basic health needs of people with his disorder.

There is no known cure for celiac disease, although there are several studies of the disease being undertaken currently, with Nexpep Pty. LTD, having a treatment drug in phase 1 clinical trials as we speak. They have already discovered three different peptides that force human T cells in the immune system to treat these gluten proteins as toxins, and are currently looking to identify ways to counteract these peptides being viewed by the T cells as toxic.

90% of all people having celiac disease are asymptomatic, meaning they had no idea that they even have this disorder. They may only experience very subtle symptoms such as fatigue or anemia with relationship to the disorder, whereas severe cases of the disease shows symptoms of diarrhea, weight loss, and failure to gain weight in young children.

Strict adherence to a gluten-free diet is the only current method of treatment available for sufferers of celiac disease, and as little as 15mg of gluten consumed in one sitting can wreak havoc a person suffering from this disorder.

Article by Jim Donahue