Skin Disorder Breakthrough Therapy Shows Promising Results

Epidermolysis bullosa or EB is a genetic condition that causes the skin to be fragile and blister

Skin Disorder

Epidermolysis bullosa or EB is a genetic condition that causes the skin to be fragile and blister easily. Recently a breakthrough therapy for this rare skin disorder from Scioderm has shown promising results.

The CEO of Scioderm, Robert Ryan has spent more than two years approaching capitalists with a strategy for treating this rare skin disease and finally raised $16 million to continue the experimental breakthrough treatment. The key strategy is the level of insurance cover. Ryan said the average insurance payment for medications to treat this rare disease is $60,000 a year per patient. He justified the cost by saying it is cheaper than the alternative, numerous bandaging, pain killers and potential hospital visits that are needed to deal with the skin wounds that proved to be resistant to healing.

Robert Ryan has continuously showed images of children who look like burn victims, covered in blisters, with open and festering sores. The blistering primarily affects the hands and feet in mild cases. Severe cases of this widespread blistering can lead to infections and other medical problems EB may be life threatening in infancy.

One can hardly notice the little fingers. Often these children are referred to as ‘butterfly children’ because of their fragile skin and many do not live past childhood.

The experimental treatment by Scioderm for Epidermolysis bullosa, or EB, the rare skin condition, which has no known cure is generating attention from nonprofit organizations dedicated to EB and the Research Association of America. The impact of this product has received a breakthrough designation form the US Food and Drug Administration and this would indeed expedite the development of this product, as the cream has demonstrated the substantial improvement of this condition.

Scioderm have provisionally called the cream SK-101 and this cream causes the wounds to heal quicker than normally. It does not treat the underlying genetic cause of the disorder, which prevents the skin layers from binding property and resulting in a fragile skin that causes excruciating pain, eating complications and unbearable itching.

Reported EB cases in America are estimated at 40,000, some have tried genetic therapy such as bone marrow transplants but only show a limited success. Many of the victims are bandaged to cover their wounds in public to prevent exposure and further tearing. EB remains a reclusive disease and not widely reported on thus few people know about the horrors of the disorder. Not all-public contact with EB patients need be repulsive.

The company Scioderm currently has six people on its team, and is planning to conduct another trial on 28 patients this summer. The third and final test planned for nearly 100 patients is expected to be concluded next year. The product will only be sold commercially after these final tests have been conducted.

Definite quality of life changes for these young children through the breakthrough therapy of this rare skin disorder by the company Scioderm, and their determination to bring positive healing change to a serious medical need that so few know about.

Written by Laura Oneale

2 Responses to Skin Disorder Breakthrough Therapy Shows Promising Results

  1. Tash June 8, 2013 at 4:16 pm

    Wow how exciting! please may this be a start to something really big and wonderful for all you kids and people with EB. x

  2. Valerie Short June 8, 2013 at 12:45 pm

    Hi Laura This is fantastic news. My son is 19 yrs old and ready to go off to college in the fall. (yikes!) We would really be interested in possibly being in this clinical trial. Any info of where this would be or others details would be appreciated.


We will read your comment immediately so leave a remark!

RSS Guardian Express

  • Miley Cyrus: Next Star to Rehab? April 21, 2014
    Miley Cyrus was reported to have told Dolly Parton about her drug use. Parton was concerned for Cyrus after hearing her talk so casual about the use. Is it possible Miley Cyrus will be the next star to go down the rabbit hole of addiction, ending up in rehab? After the outlandish behavior of Cyrus, […]
    Jabar Morarend
  • Innocence Lost Regained April 21, 2014
    Innocence in America in times past, seemed inevitable that the days of black and white would fade into color and reel to reel would evolve into the Blue Ray DVD. Yesteryear, movies were pretty tame in comparison to today’s films with their graphic violence and soft-core porn love scenes. Where are the days of Matt […]
    John Thomas
  • Turn on AMC: Of Cabbages and Kings (Recap/Review) April 21, 2014
    On Turn on AMC tonight, the episode is called Of Cabbages and Kings. The title is likely taken from the Lewis Carroll poem “The Walrus and the Carpenter.” It’s an apropos title, as Abe Woodhull is a cabbage farmer, and the show depicts Americans revolting against the rule of King George III of England, and […]
    Douglas Cobb
  • ‘Hearthstone’ Hits the iPad After Successful Beta April 21, 2014
    Hearthstone: Heroes of Warcraft, Blizzard’s crack at a collectible card game, has received rave reviews since its inception. The game was designed with the mobile platform in mind, and after months of open beta on the PC, Blizzard released the game on the iPad on Wednesday. In less than a week, Hearthstone has already become […]
    Jonathan Gardner
  • Ukraine Crisis Has Rapture Watchers Nervous [Video] April 21, 2014
    The Ukraine Crisis is continuing to draw various interests and concerns from across the world to a head. Notably, the recent events in Eastern Europe has made some rapture watchers nervous. With controversial figures and internet videos touting the recent events as prophecy, the crisis now has a heavy religious following. Figures such as John […]
    Brett Byers-Lane

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 627 other subscribers