Zack Greinke hasn’t been the difference-maker yet that the Angels were hoping for when they gave up some top prospects to get Greinke from Milwaukee. The Halos have lost both of Greinke’s starts and he has a 5.14 ERA as he takes the mound Wednesday in Oakland.
Minnesota at Cleveland – Twins LHP Brian Duensing (2-6, 4.39) vs. Indians RHP Justin Masterson (7-10, 4.78): Duensing was hurt by an error that led to three runs, but otherwise pitched well against the Red Sox on Friday. The lefty gave up five runs (two earned) on 10 hits over six innings, but got a no-decision. … Masterson suffered his second straight subpar start last time out, giving up seven runs on 10 hits in just four innings of a road loss against Detroit. Over his past two outings, the sinkerballer has gone 0-2 with a 13.97 ERA (15 ER/9 2/3 IP).
Texas at Boston – Rangers LHP Matt Harrison (13-6, 3.17) vs. Red Sox RHP Josh Beckett (5-9, 4.54): Harrison snapped a two-game losing streak by beating the Royals on Friday and is 2-3 with a 3.19 ERA in his last five games. He is 9-3 with a 2.99 ERA in 12 starts on the road this year and is 3-1 all-time against the Red Sox. … Beckett missed a start Sunday after leaving his last outing in the third inning with back spasms. In two starts against the Rangers this year, the right-hander is 0-2 with a 4.50 ERA. The Red Sox are 7-11 when Beckett takes the mound.
LA Angels at Oakland – Angels RHP Zack Greinke (9-4, 3.61) vs. A’s RHP Dan Straily (0-0, 1.50): Greinke has started twice since joining the Angels and the results have been mixed. He went seven innings in both, but picked up a loss while allowing just two runs against Tampa Bay and then allowed six earned runs vs. Chicago in a no-decision. … Straily took a no-decision in his impressive Major League debut on Friday, when he allowed one run on five hits with a walk and five strikeouts in six innings against the Blue Jays.
NY Yankees at Detroit – Yankees LHP CC Sabathia (11-3, 3.53) vs. Tigers RHP Anibal Sanchez (6-8, 3.99): Sabathia allowed one hit through the first eight innings his last time out until a homer in the ninth tarnished an impressive line. He still went the distance against Seattle and struck out 10, allowing three runs. He’s 2-0 this year against Detroit. … After allowing five runs to Toronto in his Tigers debut, Sanchez rebounded with six-plus innings, allowing two runs (one earned) vs. Cleveland at home. Next he’ll duel CC Sabathia and a Yankees lineup he hasn’t seen since his MLB debut in 2006.
Seattle at Baltimore – Mariners RHP Kevin Millwood (4-9, 4.01) vs. Orioles RHP Tommy Hunter (4-7, 5.55): Millwood pitched pretty well again on Friday but lost to the Yankees after allowing four runs in six innings. The veteran is 1-5 with six no-decisions and a 4.25 ERA over his last 12 starts while not getting much run support. … Hunter again fell victim to home runs, giving up two earned runs on six hits and a walk with three strikeouts in 5 2/3 innings in a loss to Tampa Bay.
Toronto at Tampa Bay – Jays RHP Carlos Villaneuva (6-1, 3.19) vs. Rays RHP Alex Cobb (5-8, 4.60): In his last outing, Villanueva finally lost his first game since entering the rotation — after going 4-0 over his first five starts. The right-hander allowed four runs in six innings against the Mariners and struck out six. … Cobb picked up his fifth win on Wednesday, holding the Athletics to one run on four hits in seven innings. He will be making his first start against the Blue Jays. Cobb is 3-6 with a 4.81 ERA in 12 career starts at Tropicana Field.
Kansas City at Chicago – Royals RHP Jeremy Guthrie (3-12, 6.56) vs. White Sox LHP Jose Quintana (4-1, 2.80): Guthrie had the best of his three outings, all losses, since joining the Royals from the Rockies, giving up three runs on six hits and two walks against the Rangers. He’s faced the White Sox 12 times, going 3-5. … The White Sox are taking advantage of their six-man rotation to give the rookie hurler a little extra rest. Quintana, who has allowed eight runs on 18 hits in the last 13 1/3 innings, will have eight days between starts.