Alzheimer’s Disease: Women More Susceptible Than Men

Its Official Women Are More Prone Than Men in Developing Alzheimer's Disease

There are one hundred billion nerve cells (neurons) within our brain, linking the many forms of communication networks of the body. Several groups of nerve cells have specific functions, such as thinking, remembering, and learning. Other groups help us to smell, see and hear.

Imagine the brain as a factory at work almost twenty-four hours a day, receiving supplies, generating energy, constructing things and waste removal. Then there is the process and storing of information and communicating with other nerve cells. The work function keeps everything moving perfectly, but it does require co-ordination and oxygen.

Researchers have discovered plaques and tangles, two abnormal structures which are the prime suspects in causing damage and killing nerve cells within the brain. Plaques are deposits of a protein fragment called beta-amyloid that builds up in the spaces between nerve cells and tangles are bent fibers of another protein called tau that tend to build up inside of the cells.

As people age, they develop plagues and tangles and those diagnosed with Alzheimer’s are found to generate far more. A recent study has shown that the plagues and tangles are developed in a conventional method and expand in areas critical to memory before dispersing into other areas of the brain. It is not sure what roles these two abnormal structures exactly have but scientist believe they play a vital role in closing the connections among nerve cells and disturbing the procedure that cells need to survive.

With every moving and working nerve cell running well, and when an unexpected failure occurs in the process an onslaught of problems can occur. Scientists believe microscopic changes in the brain appear long before Alzheimer’s illness prevents part of the cells from functioning properly. The damage and death of nerve cells are the main course of memory malfunction and other dementia symptoms of Alzheimer’s disease.

They are not sure where the trouble starts and ongoing research will help us to learn more about this disease. As the damage spreads, cells begin to lose their ability to work well and eventually die causing irreversible changes in the brain.

A recent study had concluded that women develop symptoms of Alzheimer’s disease at a faster rate than men do. A study conducted on Alzheimer’s sufferers of both sexes found that men with the problem regularly outperform women on tests that measured a senior’s memory capacity and their ability to perform verbal, distance and depth tasks.

Research indicates that women are more likely to be diagnosed with Alzheimer’s disease than men are and the investigation into this research has been sparse and inconsistent. This present study aimed to get a clearer understanding of gender based differences and the possible causes of these disparities.

Several indications point to the cause of greater susceptibility among women than among men. Hormones play an enormous role in making women more susceptible to Alzheimer’s and studies have shown that estrogen may serve as a shield against the disease.

Men have proved to be more powerful and have cognitive reserves which act as a buffer against the symptoms of Alzheimer’s and other forms of dementia. It appears that men have more exposure to reserve building activities than women do.

Another factor considered is the genes and primary genetic risk factor for Alzheimer’s disease, the APOE genotype has proved to be more damaging on the cognitive functioning of women than men.

Alzheimer’s is at the forefront of biomedical research today, and many possible approaches are currently investigated worldwide.

Researchers are uncovering many aspects of the disease and related dementia as possible. Some of the most remarkable progress has shed light on how Alzheimer’s affects the brain. It appears that women are more susceptible than men. A better understanding of how this works will lead to improved ways of dealing with this disease.

Written by Laura Oneale

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One Response to "Alzheimer’s Disease: Women More Susceptible Than Men"

  1. Max Wallack   August 17, 2013 at 1:11 pm

    I believe it is important for children to understand Alzheimer’s disease so they can still interact lovingly with family members who have this disease. I am a 17 year old college junior, Alzheimer’s researcher, and Alzheimer’s advocate.I grew up as a caregiver to my great grandmother who had Alzheimer’s disease. After her death, I founded a nonprofit organization that has distributed over 24,000 puzzles to Alzheimer’s facilities. Recently, the book I coauthored explaining Alzheimer’s disease to children became available on Amazon.My hope was to provide some helpful coping mechanisms to the many children dealing with Alzheimer’s disease among their family members. 50 percent of the profits from this book will go to Alzheimer’s causes. I think this book could help a lot of children and families.”Why Did Grandma Put Her Underwear in Refrigerator? A Book Explaining Alzheimer’s Disease to Children.”

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