Fibromyalgia Mystery Finally Solved!

Researchers Find Main Source of Pain in Blood Vessels

Fibromyalgia Mystery Finally Solved! Researchers Find Main Source of Pain in Blood Vessels

Researchers have found the main source of pain in Fibromyalgia patients, and contrary to what many believe, it does not stem from the brain. The findings mark the end of a decades-old mystery about the disease, which many doctors believed was conjured in patients’ imaginations. The mystery of Fibromyalgia has left millions of sufferers searching for hope in pain medications. Up until recently, many physicians thought that the disease was “imaginary” or psychological, but scientists have now revealed that the main source of pain stems from a most unlikely place- excess blood vessels in the hand.

The discovery may lead to new treatments and perhaps even a total cure in the future, bringing relief to as many as 5 million Americans thought to have the disease. To solve the Fibromyalgia mystery, researchers zeroed in on the skin from the hand of one patient who had a lack of the sensory nerve fibers, causing a reduced reaction to pain. They then took skin samples from the hands of Fibromyalgia patients and were surprised to find an extremely excessive amount of a particular type of nerve fiber called arteriole-venule (AV) shunts.

Up until this point scientists had thought that these fibers were only responsible for regulating blood flow, and did not play any role in pain sensation, but now they’ve discovered that there is a direct link between these nerves and the widespread body pain that Fibromyalgia sufferers feel.

The breakthrough also could solve the lingering question of why many sufferers have extremely painful hands as well as other “tender points” throughout the body, and why cold weather seems to aggravate the symptoms. In addition to feeling widespread deep tissue pain, many Fibromyalgia patients also suffer from debilitating fatigue.

Neuroscientist Dr. Frank L. Rice explained: “We previously thought that these nerve endings were only involved in regulating blood flow at a subconscious level, yet here we had evidences that the blood vessel endings could also contribute to our conscious sense of touch… and also pain,” Rice said. “This mismanaged blood flow could be the source of muscular pain and achiness, and the sense of fatigue which are thought to be due to a build-up of lactic acid and low levels of inflammation fibromyalgia patients. This, in turn, could contribute to the hyperactivity in the brain.”

Current treatments for the disease have not brought complete relief to the millions of sufferers. Therapies include narcotic pain medicines; anti-seizure drugs, anti-depressants and even simple advice such as “get more sleep and exercise regularly.” Now that the cause of Fibromyalgia has been pinpointed, patients are looking forward to an eventual cure. Other expressed frustration about how much they had suffered already:

“When are they ever going to figure out that things are never “all in your head?” said one commenter. “Whenever something doesn’t fit in their tiny little understanding, they belittle the patient and tell them they are crazy. People have suffered through this since they were invented. Prescribing SSRIs for everything is not the answer any more than a lobotomy or hysterectomy was.”

The announcement has the potential to unlock better future treatments and undoubtedly has patients all over the world rejoicing that the mystery of Fibromyalgia has finally been solved.

RELATED: Fibromyalgia: Proof of Physical Origins Vs. Two Danish Psychiatrists

By: Rebecca Savastio

Source: Redorbit


Source: Yahoo News

2,498 Responses to Fibromyalgia Mystery Finally Solved!

  1. Robin Edwards December 20, 2014 at 9:28 am

    was diagnosed in 1989 w chronic fatigue and fibro. It was really terrible back then because many Drs thought, it was something to give a patient so they could kick back and relax and know they werent crazy…I went to a rheumatoid specialist and he was so nice and understood it better than anyone Ive ever been to. Its not just in your head! Its real. Live it and you will understand. i would love to see something that would help this.

  2. Donna December 15, 2014 at 4:16 pm

    God help us all this IS truly the most painful REAL thing about 8 yrs ago I was diagnosed I had to be carried to the doc I was out of control pain so intense I could not walk craziest thing this doc knew what it was and had actually just started intensive research on fibro so many many diff drugs later and then stopping them all I still suffer so so so bad doc,s think I’m faking it can not get pain meds crying hysterically barely walk they won’t give me anything for relief then I start feeling like they think I’m a druggy or just want pain drugs and I’m just acting sometimes I do feel like I’m a druggy going in desperately asking for drugs or a big fat shot of pain killers right then and there!! Please let it be true they have found a cause and we can finally get some relief and have some kind of life finally
    Every night I stress out knowing I will be up most the night trying to rub the pain from my body so I can maybe get some sleep but all night I find the pressure points and rub hoping like crazy will help or relieve the pain just a little then I’m just exhausted in morning then the cycle starts all over again it’s pure he’ll please let it be true they found the cause and hope docs will be able to help us!!!!!! God bless u all and hang in there

  3. Hilda Scott December 14, 2014 at 7:47 pm

    OMG it would be wonderful to find a cure for fibromyalgia and chronic fatique!

  4. Tom Speed December 14, 2014 at 4:14 am

    Fibro, along with Migraines and I.B.S, have now been “CONFIRMED” to be caused by Endo-Cannabinoid Deficiencies:

    Clinical endocannabinoid deficiency (CECD) revisited: can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

    Smith SC, Wagner MS.


    OBJECTIVES: Ethan B. Russo’s paper of December 1, 2003 explored the concept of a clinical endocannabinoid deficiency (CECD) underlying the pathophysiology of migraine, fibromyalgia, irritable bowel syndrome and other functional conditions alleviated by clinical cannabis.

    METHODS: Available literature was reviewed, including searches via the National Library of medicine database and other sources.

    RESULTS: A review of the literature indicates that significant progress has been made since Dr. Ethan B. Russo’s landmark paper, just ten years ago (February 2, 2004). Investigation at that time suggested that cannabinoids can block spinal, peripheral and gastrointestional mechanisms that promote pain in headache, fibromyalgia, irritable bowel syndrome and muscle spasm.

    CONCLUSION: Subsequent research has ***confirmed*** that underlying endocannabinoid deficiencies indeed play a role in migraine, fibromyalgia, irritable bowel syndrome and a growing list of other medical conditions. Clinical experience is bearing this out. Further research and especially, clinical trials will further demonstrate the usefulness of medical cannabis. As legal barriers fall and scientific bias fades this will become more apparent.”

  5. Jan December 12, 2014 at 5:20 am

    I have been struggling with fibro for years and getting people to understand is very difficult as you look normal on the outside they think it is not as bad as it really is. Pain clinic have me on a cocktail of drugs everything from morphine to Gabapentin I some times wonder which is worse coping with the pain or being out of it with medication. I hope and pray that a real solution comes along soon then we may all get a quality of life


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